2010 Publications

Aden N, Nuttall A, Shiwen X, de Winter P, Leask A, Black CM, Denton CP, Abraham DJ and Stratton RJ
Epithelial Cells Promote Fibroblast Activation via IL-1α in Systemic Sclerosis
Journal of Investigative Dermatology, May 2010

Becker S, Wandel E, Wobus M, Schneider R, Amasheh S, Sittig D, Kerner C, Naumann R, Hamann J, Aust G
Overexpression of CD97 in Intestinal Epithelial Cells of Transgenic Mice Attenuates Colitis by Strengthening Adherens Junctions
Public Library of Science, January 2010, Vol. 5, No. 1, pp.1-11
PMID: 20084281

Boon RA, Leyen TA, Fontijn RD, Fledderus JO, Baggen JMC, Volger OL, van Nieuw Amerongen GP, and Horrevoets AJG
KLF2-induced actin shear fibers control both alignment to flow and JNK signaling in vascular endothelium
Journal of the American Society of Hematology, March 2010, Vol. 115, No. 12, pp. 2533-2542
PMID: 20032497

Carvajal-Vergara X, Sevilla A, D’Souza SL, Ang Y, Schaniel C, Lee DF, Yang DF, Kaplan AD, Adler ED, Rozov R, Ge YG, Cohen N, Edelmann LJ, Chang B, Waghray A, Su J, Pardo S, Lichtenbelt KD, Tartaglia M, Ge BD, and Lemischka IR
Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome
Nature Letter, June 2010, Vol. 465, pp. 808-812
PMID: 20535210

Cui X, Jin Y, Poudyal D, Chumanevich A, Davis T, Windust A, Hofseth AB, Wu W, Habiger J, Pena EA, Wood PA, Nagarkatti M, Nagarkatti P, and Hofseth LJ
Mechanistic insight into the ability of American ginseng to suppress colon cancer associated with colitis
Carcinogenesis, August 2010, Vol. 10, pp. 1734-1741
PMID: 20729391

Dufour A, Zucker S, Sampson N, Kuscu C, and Cao J
Role of matrix metalloproteinase-9 (MMP-9) dimers in cell migration
The Journal of Biological Chemistry, September 13, 2010, Vol. 285, pp. 35944-35956
PMID: 20837483

Eriksen KW, Woetmann A, Skov L, Krejsgaard T, Bovin LF, Hansen ML, Grønbæk K, Billestrup N, Nissen MH, Geisler C, Wasik MA and Ødum N
Deficient SOCS3 and SHP-1 Expression in Psoriatic T Cells
Journal of Investigative Dermatology, June 2010, Vol. 130, pp. 1590-1597
PMID: 20130595

Faustino SR, Maddaford TG , and Pierce GN
Mitogen activated protein kinase at the nuclear pore complex
Journal of Cellular and Molecular Medicine, May 2010, Epub ahead of print
PMID: 20497490

Guerrouahen BS, Futami M, Vaklavas C, Kanerva J, Whichard ZL, Nwawka K, Blanchard EG, Lee FY, Robinson LJ, Arceci R, Kornblau SM, Wieder E, Cayre YE and Corey SJ
Dasatinib Inhibits the Growth of Molecularly Heterogeneous Myeloid Leukemias
Clinical Cancer Research, February 2010, Volume 16, No. 4, pp. 1149-1158
PMID: 20145167

Hao Y, Du Q, Chen X, Zheng Z, Balsbaugh JL, Maitra S, Shabanowitz J, Hunt DF, and Macara IG
(Phosphonet reference) Par3 Controls Epithelial Spindle Orientation by aPKC-Mediated Phosphorylation of Apical Pins
Current Biology, October 2010, Vol. 20, pp. 1809–1818
PMID: 20933426

Hernandez M, Lachmann A, Zhao S, Xiao K, Ma'ayan A
Inferring the Sign of Kinase-Substrate Interactions by Combining Quantitative Phosphoproteomics with a Literature-Based Mammalian Kinome Network
Molecular Networks, April 2010, pp. 180-184

Hewel JA, Liu J, Onishi K, Fong V, Chandran S, Olsen JB, Pogoutse O, Schutkowski M, Wenschuh H, Winkler DFH, Eckler L, Zandstra PW, and Emili A
Synthetic Peptide Arrays for Pathway-Level Protein Monitoring by Liquid Chromatography - Tandem Mass Spectrometry
Molecular and Cellular Proteomics, May 2010, Volume 9, pp. 2460 – 2473
PMID: 20467045

Kelkel M, Jacob C, Dicato M and Diederich M
Potential of the Dietary Antioxidants Resveratrol and Curcumin in Prevention and Treatment of Hematologic Malignancies
Molecules, October 2010, Vol. 15, pp.7035-7074
PMID: 20944521

Kim A, Joseph S, Khan A, Epstein CJ, Sobel R, Huang TT
Enhanced expression of mitochondrial superoxide dismutase leads to prolonged in vivo cell cycle progression and up-regulation of mitochondrial thioredoxin
Free Radical Biology & Medicine, June 2010, Volume 48, No. 11, pp. 1501–1512

Kim DJ, Park KS, Kim JH, Yang SH, Yoon JY, Han BG, Kim HS, Lee SJ, Jang JY, Kim KH, Kim MJ, Song JS, Kim HJ, Park CM, Lee SK, Lee BI, and Suh SW
Helicobacter pylori proinflammatory protein upregulates NF-κB as a cell-translocating Ser/Thr kinase
Proceedings of the National Academy of Sciences of the United States of America, October 2010, Vol 107, No. 50, pp. 21418-21423
PMID: 21098302

Kozloski GA, Carothers Carraway CA, Carraway KL
Mechanistic and Signaling Analysis of Muc4–ErbB2 Signaling Module: New Insights into the Mechanism of Ligand-Independent ErbB2 Activity
Journal of Cellular Physiology, April 2010, Vol 224, pp.649-657
PMID: 20432461

Li Y, Xu FL, Lu J, Saunders WS and Prochownik EV
Widespread Genomic Instability Mediated by a Pathway Involving Glycoprotein Ib alpha and Aurora B Kinase
The Journal of Biochemistry, February 2010, Volume 285, No.17, pp. 13183
PMID: 20157117

Meltzer KR, Cao TV, Schad JF, King H, Stoll ST, Standley PR
In vitro modeling of repetitive motion injury and myofascial release
Journal of Bodywork and Movement Therapies, April 2010, Volume 14, No. 2, pp. 162-171
PMID: 20226363

Mendoza-Rincon JF, Gonzalez-Robles A, Lopez-Marure R; Caceres-Cortes JR
Enhanced Activity of pSTAT-3 Ser-727 in Functional Endothelial Cells Under Calcifying Conditions
Current Chemical Biology, May 2010, Volume 4, No. 2, pp. 133-144

Millard M, Pathania D, Shabaik Y, Taheri L, Deng J, Neamati N
Preclinical Evaluation of Novel Triphenylphosphonium Salts with Broad-Spectrum Activity
PloS One, October 2010, Vol. 5, No. 10, pp e13131
PMID: 20957228

Mobley S, Shookhof JM, Foshay K, Park M, and Gallicano GI
PKG and PKC Are Down-Regulated during Cardiomyocyte Differentiation from Embryonic Stem Cells: Manipulation of These Pathways Enhances Cardiomyocyte Production
Stem Cells International, Volume 2010, 10 pages
PMID: 21048852

Muratoglu SC, Mikhailenko I, Newton C, Migliorini M, and Strickland DK
Low Density Lipoprotein Receptor-related Protein 1 (LRP1) Forms a Signaling Complex with Platelet-derived Growth Factor Receptor-β in Endosomes and Regulates Activation of the MAPK Pathway
Journal of Biological Chemistry, May 2010, Volume 285, pp. 14308-14317
PMID: 20220145

Nandy D, Asmann YW, Mukhopadhyay D, and Basu A
Role of AKT-Glycogen Synthase Kinase axis in Monocyte Activation in Humans with and without Type 2 Diabetes
Journal of Cellular and Molecular Medicine, June 2010, Vol. 14, No (6B), pp. 1396–1407
PMID: 19754670

Sales KJ, Grant V, Catalano RD and Jabbour HN
Chorionic gonadotropin regulates CXCR4 Expression In Human Endometrium
Via E-Series Prostanoid Receptor 2 signalling to PI3K-ERK1/2: implications for
fetal-maternal cross-talk for embryo implantation
Molecular Human Reproductive, August 12, 2010, advance access
PMID: 20705717

Scherbik SV and Brinton MA
Virus-Induced Ca2_ Influx Extends Survival of West Nile Virus-Infected Cells
Journal of Virology, September 2010, Vol.84, No.17, pp8721-8731
PMID: 20538858

Volate SR, Kawasaki BT, Hurt EM, Milner JA, Kim YS, White J and Farrar WL
Gossypol Induces Apoptosis by Activating p53 in Prostate Cancer Cells and Prostate Tumor–Initiating Cells
Molecular Cancer Therapeutics, February 2010, Volume 9, No 2, pp. 461
PMID: 20124455

Xu B, Yang L, Lye RJ and Hinton BT
p-MAPK1/3 and DUSP6 regulate epididymal cell proliferation and survival in a region-specific manner
Biology of Reproduction, November 2010, Vol 83, No. 5, pp. 807-817
PMID: 20650883

Yu X, Gilden D, Schambers L, Barmina O, Burgoon M, Bennett J, Owens G.
Peptide reactivity between multiple sclerosis (MS) CSF IgG and recombinant antibodies generated from clonally expanded plasma cells in MS CSF.
Journal of Neuroimmunology, December 2010, Article in Press (Volume and pagination TBA)
PMID: 21176973

Zhang M, Brewer AC, Schröder K, Santos CXC, Grieve DJ, Wang M, Anilkumar N, Yu B, Dong X, Walker SJ, Brandes RP, and Shah AM
NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis
Proceedings of the National Academy of Sciences of the United States of America, October 2010, Vol. 107, No. 42, pp.18121-18126
PMID: 20921387