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Protein 3D Structures

Complexes of Signal Transduction Proteins and Molecular Machines

These are high resolution images of the 3D x-ray crystallographic structures of signalling proteins and other proteins in multimeric complexes. Animated versions of these proteins can be downloaded from the Animations page of this website. These images appeared originally in our 2004 Calendar, which was designed by Cameron Bowyer. (ADOBE PDF FORMAT)

 Adenylate Cyclase C1A and C2A Domains and Gs-alpha Complex, and G-beta/gamma and G protein-Receptor Kinase 2 Complex
 Cyclin-dependent Kinase 2, Cyclin A and p27 Kip Inhibitor Complex.
 Nucleosome Histone H2A.1, H2B.2, H3 and H4-DNA Complex
 Calmodulin-dependent Kinase 2 and Calmodulin Complex
 Bacterial 50S and 30S Ribosomal Protein Complexes with rRNA
 RNA Polymerase II Complex
 Trail/Apo2 Ligand and Death Receptor 5 Extracellular Domain Complex
 Caspase 7 and Xenopus Inhibitor of Apoptosis Protein XIAP Complex
 T Cell Receptor – Major Histocompatibility Complex
 Epidermal Growth Factor (EGF) and EGF Receptor Complex
 Tumour Suppressor Protein p53 and DNA Complex
 Erythropoietin (Epo) and Epo Receptor Extracellular Domain Complex
 Bone Morphogenetic Protein 2 (BMP-2) and BMP Receptor 1A Extracellular Domain Complex.