Our services
unique, integrated, unparalled.
Kinexus is striving to revolutionize the discovery-based research paradigm so that all researchers can access and benefit from taking a systems biology, proteomics approach to investigate their experimental model systems.
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Services Map
We have created a powerful discovery engine that is unparalleled for the generation and analysis of quantitative proteomics data based on the application of over 1800 highly validated antibodies.
Each of the unique services
offered by Kinexus are highly integrated and permit our clients to:
In the past, researchers had to make intelligent guesses as to which of hundreds of signalling proteins may be relevant in their studies, gambled on which costly antibodies to procure to track these proteins, and trusted that their experiments were performed in-house without any other technical issues.
Often the equipment required for proteomics research is beyond the financial means of the average lab.
Kinexus has minimized the risks and maximized the prospects for research success by providing our unique suite of antibody-based proteomics and bioinformatics services to over 3,000 academic and industrial labs for over 26 years.
We offer protein identification services to identify interesting antibody-cross reactive proteins by mass spectrometry.
Due to the high variation of protein expression and phosphorylation that can arise in biological specimens, to identify the most robust and reliable biomarkers, it may be necessary to validate the biomarkers in hundreds of clinical samples.
Our Custom Kinex™ Reverse Lysate Macroarray Services Array Service permits such evaluations.
Our unique, integrated platform of proteomics services can take your research to new heights.
The results from thousands of Kinex™ and Kinetworks™ analyses performed over the last 26 years are available through our open-access KiNET-AM database and on the Products section of this website.
Over 95% of this immunoblotting and antibody microarray data is unavailable elsewhere.
Clients have unlimited use of KiNET to query about the expression levels and phosphorylation states of hundreds of target proteins in hundreds of well defined experimental models systems.
- Perform broad analyses for over 949 different signalling proteins, and thousands of phosphosites with cell and tissue lysates [Antibody Microarray];
- Validate the probes for their most interesting data by immunoblotting [Kinetworks™ Services];
- Identify antibody cross-reactive proteins and global protein phosphorylation [Mass Spectrometry Services];
- Validate the biomarker leads with biological replicates for their most interesting data [Custom Kinex™ Reverse Lysate Macroarray Services];
- Identify protein and peptide substrates of kinases by in silico prediction [Kinase Substrate In Silico Prediction] and endogenous cell and tissue lysate proteins in vitro with purified kinases and phosphatases with high content antibody microarray, peptide microarray and mass spectrometry approaches [Substrate Profiling Services];
- Obtain custom peptides in powder form or on arrays [Custom Peptide and SPOT Array Services ];
- Obtain custom, affinity-purified rabbit polyclonal antibodies [Custom Antibody Services];
- Have presentation and publication ready figures produced based on their results [Custom Graphics Services].
In the past, researchers had to make intelligent guesses as to which of hundreds of signalling proteins may be relevant in their studies, gambled on which costly antibodies to procure to track these proteins, and trusted that their experiments were performed in-house without any other technical issues.
Often the equipment required for proteomics research is beyond the financial means of the average lab.
Kinexus has minimized the risks and maximized the prospects for research success by providing our unique suite of antibody-based proteomics and bioinformatics services to over 3,000 academic and industrial labs for over 26 years.
We offer protein identification services to identify interesting antibody-cross reactive proteins by mass spectrometry.
Due to the high variation of protein expression and phosphorylation that can arise in biological specimens, to identify the most robust and reliable biomarkers, it may be necessary to validate the biomarkers in hundreds of clinical samples.
Our Custom Kinex™ Reverse Lysate Macroarray Services Array Service permits such evaluations.
Our unique, integrated platform of proteomics services can take your research to new heights.
The results from thousands of Kinex™ and Kinetworks™ analyses performed over the last 26 years are available through our open-access KiNET-AM database and on the Products section of this website.
Over 95% of this immunoblotting and antibody microarray data is unavailable elsewhere.
Clients have unlimited use of KiNET to query about the expression levels and phosphorylation states of hundreds of target proteins in hundreds of well defined experimental models systems.
Using
KiNET-AM and the immunoblots shown in our
Products section, clients can plan out their future cell signalling studies based on previously unpublished findings.
They can also compare their own Kinetworks™ and Kinex™ results with the data from thousands of other experiments performed and analyzed with the very same methods, reagents, equipment and personnel.
Kinexus can also perform custom queries of our databases for clients upon request.
We offer in vitro protein kinase-based services to foster drug discovery research.
With our Custom Kinase-Substrate Identification Services, clients can have Kinexus identify panels of physiological substrates for over 360 different protein kinases in the lysates from cells and tissues provided by our customers.
This analysis also includes tentative identification of phosphorylation sites and phosphosite antibodies that permit detection of the kinase substrates.
Our DrugKiNET knowledgebase allows our clients to find previously unidentified off-target protein kinases for hundreds of existing, known kinase inhibitory compounds.
Based on analysis of our on-line SigNET databases, clients may wish to obtain purified preparations peptides and antibodies.
These are available to our customers throughout Custom Peptide and Antibody Production Services.
These services permit optimization of peptide substrates for kinases and phosphatases, the creation of peptides for antibody production, and epitope mapping of the resultant antibodies.
Finally, as part of our coninuing commitment for ensuring that clients are able to fully exploit the results from our Kinetworks™ and Kinex™ proteomics services, we also provide custom Graphics, services in which we can produce publication and presentation ready figures of the results from these services.
This includes detailed protein-protein interactions maps initially prepared with Netscape software and further customized with Adobe Illustrator.
With over 538 protein kinases and 152 protein phosphatases catalyzing the reversible phosphorylation of the human proteome at potentially a million sites, the true complexity of cell signalling is only starting to become fully appreciated.
Significant breakthroughs in signal transduction research will require the type of high content proteomics analyses of biological samples that Kinexus offers. Let us be your trusted research partner for your next big discovery.
They can also compare their own Kinetworks™ and Kinex™ results with the data from thousands of other experiments performed and analyzed with the very same methods, reagents, equipment and personnel.
Kinexus can also perform custom queries of our databases for clients upon request.
We offer in vitro protein kinase-based services to foster drug discovery research.
With our Custom Kinase-Substrate Identification Services, clients can have Kinexus identify panels of physiological substrates for over 360 different protein kinases in the lysates from cells and tissues provided by our customers.
This analysis also includes tentative identification of phosphorylation sites and phosphosite antibodies that permit detection of the kinase substrates.
Our DrugKiNET knowledgebase allows our clients to find previously unidentified off-target protein kinases for hundreds of existing, known kinase inhibitory compounds.
Based on analysis of our on-line SigNET databases, clients may wish to obtain purified preparations peptides and antibodies.
These are available to our customers throughout Custom Peptide and Antibody Production Services.
These services permit optimization of peptide substrates for kinases and phosphatases, the creation of peptides for antibody production, and epitope mapping of the resultant antibodies.
Finally, as part of our coninuing commitment for ensuring that clients are able to fully exploit the results from our Kinetworks™ and Kinex™ proteomics services, we also provide custom Graphics, services in which we can produce publication and presentation ready figures of the results from these services.
This includes detailed protein-protein interactions maps initially prepared with Netscape software and further customized with Adobe Illustrator.
With over 538 protein kinases and 152 protein phosphatases catalyzing the reversible phosphorylation of the human proteome at potentially a million sites, the true complexity of cell signalling is only starting to become fully appreciated.
Significant breakthroughs in signal transduction research will require the type of high content proteomics analyses of biological samples that Kinexus offers. Let us be your trusted research partner for your next big discovery.